Biological Activities of Nitro Steroids

Dembitsky, Valery and Gloriozova, Tatyana and Poroikov, Vladimir (2017) Biological Activities of Nitro Steroids. Journal of Pharmaceutical Research International, 18 (4). pp. 1-19. ISSN 24569119

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Abstract

The present review describes the biological activities of synthetic nitro steroids. More than fifty biologically active nitro steroids showed an analeptic, antineoplastic, anesthetic, neuroprotector, immunosuppressant, dermatologic properties, and also show other biological activities. The structures and activities of a selection of nitro steroids are reported. Also, some new and additional activities are predicted with the computer program PASS, based on structure–activity relationships (SAR), which point toward new possible applications of these lipid compounds. This review emphasizes the role of the nitro steroids, as an important source of leads for drug discovery.

Item Type: Article
Subjects: East India Archive > Medical Science
Depositing User: Unnamed user with email support@eastindiaarchive.com
Date Deposited: 31 May 2023 06:45
Last Modified: 17 Oct 2024 04:17
URI: http://ebooks.keeplibrary.com/id/eprint/1154

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