An Unusual Appearance of Cystic Gastro Intestinal Stromal Tumor of Small Intestine - A Case Report and Brief Review of Literature

Gastrointestinal stromal tumor (GIST), is considered as most common mesenchymal neoplasm of the GI tract. They can arise anywhere in the gastrointestinal (GI) tract, with the gastric GIST accounting for 50% to 60% of cases, the small intestinal GIST for 20% to 30%. It arises from the interstitial cells of Cajal, which are part of the muscle plexes of the intestine.Radiologically, they are best identified by Computed Tomography (CT) scan. Grossly, GIST is a solid tumorbut infrequently shows cystic degeneration. Immunohistochemistry( IHC) shows positivity for CD117 (C-Kit), CD34, and/or DOG-1. Radical resection is currently the preferred treatment for small intestinal GISTs.During the past decade, GISTs have presented as an important model in the emerging field of molecularly targeted therapies for solid tumors. Here we report a case mutifocal GIST with unusual gross appearance of cystic degeneration.