Phytochemicals against COVID -19, Pharmacological Perspectives: A Systematic Review

Ali, Ahmed S. and Saied, Ekram A. and Theeban, Sharifa M. and Humayran, Mazen M. and Shaker, Assmaa Ahmed and Alfadil, Abdelbagi and Almuhayawi, Mohammed S. (2021) Phytochemicals against COVID -19, Pharmacological Perspectives: A Systematic Review. Journal of Pharmaceutical Research International, 33 (53B). pp. 34-55. ISSN 2456-9119

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Abstract

Background: Many publications discussed the potential role of medicinal plants in the management of COVID-19. However, clinical studies of the efficacy and safety of specified phytochemical(s) are limited.

Objectives: To explore the pharmacological profile of specified compounds against COVID-19

Method: Systematic literature search of academic databases to explore specified phytochemicals for the management of COVID-19 using appropriate search terms. Rayyan software was used to organize 786 citations of which. 236 articles were included in this review.

Results: Initially 70 compounds were identified to have a potential role in the management of COVID-19. In this review, 18 compounds were selected for further search

Conclusion: In vitro anti-SARS-CoV-2activity has been demonstrated for a variety of natural compounds. However, preclinical research for most phytochemicals is scarce, and only a few compounds have been evaluated in clinical trials against COVID-19. A comprehensive pharmacological profile of these phytochemicals is urgently needed.

Item Type: Article
Subjects: East India Archive > Medical Science
Depositing User: Unnamed user with email support@eastindiaarchive.com
Date Deposited: 17 Feb 2023 11:34
Last Modified: 01 Jul 2024 13:28
URI: http://ebooks.keeplibrary.com/id/eprint/60

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