The Effect of COVID-19 Infection on Human Blood Ghrelin Hormone: A Pilot Study

Hakami, Nora Y. and Alhazmi, Wafaa A. and Taibah, Eman O. and Sindi, Mamdouh M. and Alotaibi, Ohoud F. and Al-Otaibi, Hajed M. and Alhadrami, Hani A. (2021) The Effect of COVID-19 Infection on Human Blood Ghrelin Hormone: A Pilot Study. Journal of Pharmaceutical Research International, 33 (7). pp. 33-38. ISSN 2456-9119

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Abstract

Objectives: The pandemic of coronavirus disease 2019 (COVID-19) has been one of the major health concerns for all the countries around the globe. This study was aimed to study the potential effect of COVID-19 virus on the level of blood ghrelin appetite hormone in order to determine the influence of this infection on the patient appetite.

Methods: This is a cross-sectional study was conducted between July and the end of August 2020 in the western region of Saudi Arabia. A total of 50 confirmed positive patients with COVID-19 (positive group) and 30 control healthy subjects with negative blood samples (negative group) were collected to determine the level of ghrelin appetite hormone using the human ghrelin (GHRL) ELISA technique. A student’s t-test was carried out to find out the statistical change between different study groups.

Results: The serum total ghrelin concentrations, on average, were 51.32 pg/mL on positive group and 50.37 pg/mL on negative group, respectively. The difference of ghrelin was statistically insignificant between the two groups (P >0.05). Although the sample size of the study was small, the results showed high number of COVID-19 cases in male than female.

Conclusion: The current data shows that there are no significant changes in the level of serum ghrelin hormone in COVID-19 patients. Consequently, it might be possible that the ghrelin hormone showed potential changes in the saliva compared to the effect in the blood. Thus, a further analysis of the ghrelin hormone in the saliva of COVID-19 patients will be conducted in the near future.

Item Type: Article
Subjects: East India Archive > Medical Science
Depositing User: Unnamed user with email support@eastindiaarchive.com
Date Deposited: 03 Apr 2023 08:14
Last Modified: 12 Sep 2024 04:51
URI: http://ebooks.keeplibrary.com/id/eprint/641

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