Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index: Impaired fasting glucose in first degree relatives of Type-II diabetic patients

Muhammed, Alia Ali and Taj, Azeem and Ahmed, Muhammed Uthman and Tabrez, Elsa (2020) Frequency of impaired fasting glucose in first degree relatives of Type-II diabetic patients and its association with Body Mass Index: Impaired fasting glucose in first degree relatives of Type-II diabetic patients. Pakistan Journal of Medical Sciences, 36 (3). pp. 407-411. ISSN 1682-024X

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Abstract

Objectives: To determine the frequency of impaired fasting glucose in first degree relatives of people with Type-II diabetes and its association with BMI.

Methods: This cross-sectional study was conducted in Diabetic clinic of Shaikh Zayed Hospital, Lahore from July to December 2017. Individuals aged ≥35 years, first degree relatives of people with Type-II diabetes, were selected and their fasting blood glucose levels were checked twice a week apart. Study participants were divided into 3 groups. Group-I were those with normal fasting blood glucose (FBS: <100mg/dl), Group-II were those with impaired fasting glucose (100-125mg/dl), considered as high risk and Group-III included those who turned out to be having frank diabetes (FBS: ≥126mg/dl). Exclusion criteria were known diabetes and pregnancy. Proportions of impaired fasting glucose levels versus BMI were compared using Chi-square test. Significance was considered at P <0.001.

Results: A total of hundred subjects were included in the study with the mean age of 44.27 years. Sixty percent participants had normal FBS, 31% showed impaired FBS and 09% had frank diabetes (P <0.001). Significant association was found between impaired fasting glucose and BMI, as with increasing BMI the frequency of impaired fasting glucose increases.

Conclusion: First-degree relatives of people with Type-II diabetes showed higher frequency of impaired fasting glucose and obesity was an important risk factor.

Item Type: Article
Subjects: East India Archive > Medical Science
Depositing User: Unnamed user with email support@eastindiaarchive.com
Date Deposited: 20 Apr 2023 07:55
Last Modified: 20 Sep 2024 04:27
URI: http://ebooks.keeplibrary.com/id/eprint/910

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