Nasiri, Ehsan and Naseri, Amirreza and Yazdchi, Mohammad and Talebi, Mahnaz (2021) Is there a link between COVID-19 and Creutzfeldt-Jakob Disease? a Case Report. Journal of Research in Clinical Medicine, 9 (1). p. 26. ISSN 2717-0616
jrcm-9-26.pdf - Published Version
Download (615kB)
Abstract
Creutzfeldt-Jakob Disease (CJD) is a rare rapidly progressive neurodegenerative disease. The diagnosis of CJD is based on magnetic resonance imaging (MRI) findings, electro-encephalography (EEG), or 14-3-3 protein detection. We report a case of a previously-healthy 72 years old woman, with evidence of coronavirus disease 2019 (COVID-19), who complained of behavioral changes and rapidly progressive dementia. While hospitalization, she didn't have orientation to time and place and repeated an irrelevant sentence in response to questions. Also, anomia and impaired comprehension was observed. Myoclonic jerks, abnormal signal intensity at bilateral parieto-occipital cortices in MRI, periodic sharp wave complexes in EEG, and increased lactate dehydrogenase in cerebrospinal fluid (CSF), highly recommended CJD for her. This is the second case of CJD after COVID-19 during this pandemic, which can be an alarm to clinicians about the silent impact of COVID-19 on the central nervous system.
Item Type: | Article |
---|---|
Subjects: | East India Archive > Medical Science |
Depositing User: | Unnamed user with email support@eastindiaarchive.com |
Date Deposited: | 16 Jan 2023 10:50 |
Last Modified: | 01 Jul 2024 13:28 |
URI: | http://ebooks.keeplibrary.com/id/eprint/21 |